Know your insulin. Humalog is a rapid-acting form of insulin that should be injected below the skin within 15 minutes before or immediately after a meal. Have food ready before injection.
After injecting the insulin, do not skip a meal or delay eating. Prepare your insulin. An intermediate- or long-acting insulin is often prescribed with Humalog. Humalog can be mixed with insulin NPH intermediate-acting insulin , but always draw Humalog into the syringe first. Never mix Humalog with Lantus. Do not mix Humalog with other insulins if using an insulin pen or external pump. Do not vigorously shake insulin before use.
Don't reuse or recycle. When the container is full, seal the lid before placing it in the trash. Don't share. Even if you change the needle, sharing an insulin pen or syringe may spread diseases carried in the blood, including hepatitis and HIV.
Avoid mix-ups. If you use more than one type of insulin, make each vial or pen look different by putting a rubber band around one type of insulin.
Check your medicine. Humalog can be confused with NovoLog or Humulin other insulins. When you pick up your insulin at the pharmacy, be sure it's the right type of insulin. Treat low blood sugar hypoglycemia. Section solely to indicate this fact. National Center for Biotechnology Information , U. Journal List Diabetes Care v.
Diabetes Care. Published online Feb Weinzimer , MD 1. William V. Find articles by James Dziura. Stuart A. Author information Article notes Copyright and License information Disclaimer. Corresponding author: Eda Cengiz, ude. Received Nov 17; Accepted Jan Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.
This article has been cited by other articles in PMC. RESULTS Mixing the two insulins shifted the time action curve to the right, with significantly lower glucose infusion rate GIR values after the mixed injections between 60 and min and significantly higher values between and min, lowered the GIR max separate 7.
Procedures Subjects were admitted to the Yale—New Haven Hospital Research Unit on the evening before the euglycemic clamp to monitor blood glucose levels. Statistical analysis Statistical comparisons were performed using GraphPad Prism version 5.
Open in a separate window. Figure 1. Table 1 Pharmacodynamic and pharmacokinetic summary measures after subcutaneous injection of insulin glargine and lispro in separate or mixed injections. Figure 2. Footnotes The costs of publication of this article were defrayed in part by the payment of page charges. References 1. Lepore G, Dodesini AR, Nosari I, Trevisan R: Both continuous subcutaneous insulin infusion and a multiple daily insulin injection regimen with glargine as basal insulin are equally better than traditional multiple daily insulin injection treatment.
Lepore M, Pampanelli S, Fanelli C: Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro. Diabetes ; 49 : — [ PubMed ] [ Google Scholar ]. Insert information for Lantus, glargine. Sanofi-Aventis Lantus, data on file. Pediatrics ; : e— e [ PubMed ] [ Google Scholar ].
Mercodia Insulin Assay Insert Revised Support Center Support Center. Remember: These long-acting insulins can 't be mixed in the same syringe with other insulins — this could change how the insulin works. Insulin glargine forms clusters when it is injected under the skin. Similarly, what insulin Cannot be mixed with others? Humalog can be mixed with insulin NPH intermediate-acting insulin , but always draw Humalog into the syringe first.
Never mix Humalog with Lantus. Do not mix Humalog with other insulins if using an insulin pen or external pump. Do not vigorously shake insulin before use. Mixing Lantus and rapid-acting insulins as Humalog or Novolog does not compromise glycemic control.
The ability to give RAIs and insulin glargine in the same syringe has the potential to decrease the number of daily injections and increase use of insulin glargine , lead author Dr. A: The action time of Lantus insulin changes when it is mixed with any other insulin. You end up with some mixture of long-acting and short-acting insulin , but the mixture is unpredictable.
So the manufacturer of Lantus recommends it should not be mixed with any other type of insulin in the same syringe. What does Lantus do for diabetics? Insulin is a hormone that works by lowering levels of glucose sugar in the blood.
Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours. Lantus is used to improve blood sugar control in adults and children with diabetes mellitus. What insulins can you mix together?
The following insulins may be combined: a. Novolog Lispro and Humalog Aspart , Rapid acting insulin, can be mixed with NPH if provided by the same manufacturer and are administered within 15 minutes after mixing. Regular short acting insulin and NPH can be mixed.
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