Moreover, syringe pumps compatible with microfluidic applications are available in the market, which facilitates research in fields such as micro-environmental control. Microfluidic applications of syringe pumps have been increased dramatically in the vaccine research area.
Syringe pumps can also facilitate precise infusion in medical and biological research; for instance, feeding small animals or delivering very small doses to specific sites in the brain in neuroscience research. In industrial applications, syringe pumps can be used for scale-up, new material development, and materials characterization in chemical, pharmaceutical, catalysis, and materials science research. They can also play a major role in minimizing errors in the fields of microanalysis and instrumental analytics, such as mass spectrometry MS , high-performance liquid chromatography HPLC , and liquid chromatography-mass spectrometry LC-MS.
In conclusion, syringe pumps are useful for accelerating research and minimizing fluid delivery errors in many advanced research fields. Researchers originally developed infusion pumps, of which syringe pumps are one type, for controlled drug delivery. Christopher Wren invented the first infusion pump in , but technical limitations, botched blood transfusions, and government bans slowed development.
New prototypes appeared in the 19th century, and an infusion pump was first used for chemotherapy in the s to administer Fluorouracil, 5FU. Smaller, more cost-effective ambulatory pumps i. In particular, Dean Kamen—elected to the National Academy of Engineering in and perhaps best known for bringing the Segway to market in —invented an ambulatory infusion pump for insulin administration to diabetic patients.
In particular, combining ambulatory technology with PC communications helped researchers identify and troubleshoot problematic pump performance. For more than a period of 50 years, researchers and scientists have utilized syringe pumps, with their capability to modulate the flow of fluids on a small level, to save lives and execute high-impact research studies. Initially, scientists created infusion pumps, of which syringe pumps are one type, for controlled delivery of drugs. In , Christopher Wren developed the first infusion pump, but the development was slow due to technical restrictions, substandard blood transfusions and bans imposed by the government.
New models appeared in the 19th century, and an infusion pump was first utilized for chemotherapy in the s.
Electronic pump development, productivity upgrades, and miniaturization of the pumps in the s — s expanded the use of infusion pumps in research.
To ensure the appropriate working of the plenum vaporizer systems, it is important that the system is supplied with pressurized gas. The vaporizer must be correctly attached, and locking mechanisms must be fully engaged to avoid any leakage of the agent and the gas. Vaporizers must not be overfilled or underfilled to prevent failure of the vaporizer systems.
It is also important to ensure that the correct anesthetic agent is used to prevent over- or under-dosing the subject. Regular servicing of the vaporizer is also critical for its proper functioning.
The primary components of the digital syringe pump typically comprise of the pusher block, syringe holder, and an internal stepper motor. The pusher block contacts the plunger and initiates the flow while the motor drives the plate. The syringe holder keeps the syringe in its place during the operation of the device. The syringe pump also includes an LCD touchscreen interface that allows easy programming of flow rates and volumes.
Some models can even be linked to a computer to record the infusion history. The linear force of the syringe pump is 18kg. It includes infusion or withdrawal settings. The dimensions are 27cm x 25cm x 12 cm. The stroke rate of the device is 0. The syringe pump has a flow rate of 0. The syringe size ranges from 0. Primarily, the aim of the syringe pump is to progressively administer precise doses of a drug while controlling the flow rate.
To ensure that the syringe pump can successfully accomplish its purpose, place the device on a clean and level surface. Now, connect the power cord. Before turning the pump on, attach it to the electric switch utilizing the power cable. Attach the end of the power cord to the main socket at the back of the syringe pump.
Now take the plug and attach it to the electric mains. Turn on the mains switch. The touchscreen display will indicate that the power is connected to the pump.
The next step is to make sure that the syringe is loaded accurately. Pinch and hold together the clutch lever that releases the clutch and force the syringe driver away until it touches the end of its track. Hold the clear syringe clamp; pull upward making room for the syringe in the syringe saddle. First put in the syringe barrel. Ensure that the syringe finger tabs are held by the metal holding spring, and discharge the syringe clamp in order to hold the syringe in the saddle safely.
Pinch together the clutch lever and allow the syringe driver to progress forward until the point when the syringe driver touches the end of the disposable syringe plunger. Discharge the clutch lever so that the holding bars secure the end of the plunger to avoid siphoning. The syringe is at the moment correctly loaded. Now, the syringe pump needs to be switched on. To turn on the pump, push the on button on the keypad. The instant you turn the pump on, it undergoes a self-test displaying various characters on the screen.
When the self-test is finished, it will show on the screen. The infusion settings of the pump can be customized in a menu-driven procedure. Just choose Syringe Pump Overview on the Playlist. Syringe pumps either draw in or push out liquid through a syringe to obtain a known volume as determined by the size of the syringe.
You can depend on us for a wide selection of syringe pumps from low-flow, low-pressure applications, where precision is needed, to robust, high pressure models ideal for fluid delivery to reactors in chemical applications or for working with viscous fluids. Select pumps are available with user-friendly touch screens to help you work more efficiently. Save my name, email, and website in this browser for the next time I comment. Have any questions or comments about this article? Fill out the form below and we'll get back to you as soon as possible!
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